Preprint

Label-free mid-infrared photothermal microscopy revisits intracellular thermal dynamics: what do fluorescent nanothermometers measure?

Keiichiro Toda, Masaharu Takarada, Genki Ishigane, Hiroyuki Shimada, Venkata Ramaiah Badarla, Kohki Okabe, Takuro Ideguchi

arXiv:2406.16265

 

 

2024

Broadband coherent Raman scattering spectroscopy at 50,000,000 spectra/s

Takuma Nakamura, Kazuki Hashimoto, Takuro Ideguchi

Ultrafast Science 4, 0076 (2024)

Compressive time-stretch spectroscopy with pulse-by-pulse intensity modulation

Akira Kawai, Ryoichi Horisaki, and Takuro Ideguchi

Optics Letters 49, 3468-3471 (2024)

Mid-infrared optical coherence tomography with MHz axial line rate for real-time non-destructive testing

Satoko Yagi, Takuma Nakamura, Kazuki Hashimoto, Shotaro Kawano, Takuro Ideguchi

APL Photonics 9, 051301 (2024)

Mid-infrared wide-field nanoscopy

Miu Tamamitsu, Keiichiro Toda, Masato Fukushima, Venkata Ramaiah Badarla, Hiroyuki Shimada, Sadao Ota, Kuniaki Konishi, Takuro Ideguchi

Nature Photonics 18, 738–743 (2024) プレスリリース

Single-image phase retrieval for off-the-shelf Zernike phase-contrast microscopes

Rikimaru Kurata*, Keiichiro Toda*, Genki Ishigane, Makoto Naruse, Ryoichi Horisaki, and Takuro Ideguchi

Optics Express 32, 2202-2211 (2024)

ビデ―レート中赤外フォトサーマル生細胞イメージング(2023日本の光学研究)

石金元気、戸田圭一郎、玉光未侑、島田紘行、Venkata Ramaiah Badarla、井手口拓郎

光学 第53巻第6号, 241 (2024)

次世代の超高速赤外分光と超解像赤外顕微鏡

井手口拓郎

高分子 73巻6月号, 279-280(2024)

 

2023

Label-free mid-infrared photothermal live-cell imaging beyond video rate

Genki Ishigane*, Keiichiro Toda*, Miu Tamamitsu, Hiroyuki Shimada, Venkata Ramaiah Badarla, Takuro Ideguchi

Light: Science & Applications 12, 174 (2023) プレスリリース

Thermo-optical measurements using quantitative phase microscopy

Nicholaus Kevin Tanjaya, Keiichiro Toda, Takuro Ideguchi, and Satoshi Ishii

Optics Letters 48, 3311-3314 (2023)

Upconversion time-stretch infrared spectroscopy

Kazuki Hashimoto, Takuma Nakamura, Takahiro Kageyama, Venkata Ramaiah Badarla, Hiroyuki Shimada, Ryoich Horisaki, Takuro Ideguchi

Light: Science & Applications 12, 48 (2023) プレスリリース

世界最高速のラマン分光法

中村卓磨、橋本和樹、井手口拓郎

フォトニクスニュース 第9巻第2号, 64 (2023)

中赤外フォトサーマル定量位相顕微鏡による細胞イメージング

石金元気、戸田圭一郎、井手口拓郎

オプトロニクス 第500号,  94-98 (2023)

次世代赤外分光

井手口拓郎

現代化学 第622号,  30-31 (2023)

 

2022

Simple approach to broadband mid-infrared pulse generation with a mode-locked Yb-doped fiber laser

Takuma Nakamura, Venkata Ramaiah Badarla, Kazuki Hashimoto, Peter G. Schunemann, Takuro Ideguchi

Optics Letters 47, 1790-1793 (2022)

赤外フォトサーマル定量位相顕微鏡

井手口拓郎

レーザー研究 50巻8号,  442-446 (2022)

アダプティブダイナミックレンジシフト定量位相顕微鏡(2021年日本の光学研究)

戸田圭一郎、玉光未侑、井手口拓郎

光学 第51巻第6号, 265 (2022)

中赤外光熱ホログラフィック顕微鏡

戸田圭一郎、玉光未侑、石金元気、井手口拓郎

光学 第51巻第5号, 219-225 (2022)

 

2021

Broadband complementary vibrational spectroscopy with cascaded intra-pulse difference frequency generation

Kazuki Hashimoto, Venkata Ramaiah Badarla, Takayuki Imamura, Takuro Ideguchi

Optics Letters 46, 5517-5520 (2021)

Graphene photodetectors with asymmetric device structures on silicon chips

Kenta Shimomura, Kaname Imai, Kenta Nakagawa, Akira Kawai, Kazuki Hashimoto, Takuro Ideguchi, Hideyuki Maki

Carbon Trends 5, 100100 (2021)

Compressive dual-comb spectroscopy

Akira Kawai, Takahiro Kageyama, Ryoichi Horisaki, Takuro Ideguchi

Scientific Reports 11, 13494 (2021) 

Adaptive dynamic range shift (ADRIFT) quantitative phase imaging

Keiichiro Toda, Miu Tamamitsu, Takuro Ideguchi

Light: Science & Applications 10, 1 (2021)プレスリリースUTokyoFOCUS

High-speed Fourier-transform infrared spectroscopy with phase-controlled delay line

Kazuki Hashimoto, Venkata Ramaiah Badarla, Takuro Ideguchi

Laser & Photonics Reviews 15, 2000374 (2021)

中赤外フォトサーマル定量位相イメージング(2020年日本の光学研究)

玉光未侑、戸田圭一郎、島田紘行、本多孝明、寳田雅治、岡部弘基、長島優、堀﨑遼一、井手口拓郎

光学第50巻第6号(2021) 

中赤外フォトサーマル定量位相顕微鏡による生細胞の非標識分子イメージング

戸田圭一郎,玉光未侑,井手口拓郎 

フォトニクスニュース第6巻第4号(2021)

 

2020

Time-stretch infrared spectroscopy

Akira Kawai, Kazuki Hashimoto, Tatsuo Dougakiuchi, Venkata Ramaiah Badarla,  Takayuki Imamura, Tadataka Edamura, Takuro Ideguchi

Communications Physics 3, 152 (2020)プレスリリースUTokyoFOCUS

A multimodal laser-scanning nonlinear optical microscope with a rapid broadband Fourier-transform coherent Raman modality

Faris Sinjab, Kazuki Hashimoto, Venktata Ramaiah Badarla, Junko Omachi, Takuro Ideguchi

Optics Express 28, 20794-20807 (2020) Image of the week in OSA publisheing

Spatiotemporal monitoring of intracellular metabolic dynamics by resonance Raman microscopy with isotope labeling

Yusuke Yonamine, Kotaro Hiramatsu, Takuro Ideguchi, Takuro Ito, Tomomi Fujiwara, Yoshiko Miura, Keisuke Goda and Yu Hoshino

RSC Adv. 10, 16679-16686 (2020)

Label-free biochemical quantitative phase imaging with mid-infrared photothermal effect

Miu Tamamitsu, Keiichiro Toda, Hiroyuki Shimada, Takaaki Honda, Masaharu Takarada, Kohki Okabe, Yu Nagashima, Ryoichi Horisaki, Takuro Ideguchi

Optica 7, 359-366 (2020)プレスリリース(東京大学)UTokyoFOCUS

Enhanced spectral resolution for broadband coherent anti-Stokes Raman spectroscopy

Faris Sinjab, Kazuki Hashimoto, Xuanqiang Zhao, Yu Nagashima, Takuro Ideguchi

Optics Letters 45, 1515-1518 (2020) Editor's pick

Bioimaging by molecular-vibration-sensitive quantitative phase microscopy based on wide-field mid-infrared photothermal excitation

Miu Tamamitsu, Keiichiro Toda, Yu Nagashima, Ryoichi Horisaki, Takuro Ideguchi

Proc. SPIE 11252, Advanced Chemical Microscopy for Life Science and Translational Medicine, 112521N (21 February 2020); https://doi.org/10.1117/12.2545728 

 

 

2019

Complementary Vibrational Spectroscopy

Kazuki Hashimoto, Venkata Ramaiah Badarla, Akira Kawai, Takuro Ideguchi

Nature Communications 10, 4411 (2019),  プレスリリース(東京大学),  UTokyoFOCUS

Quantitative phase imaging with molecular vibrational sensitivity

Miu Tamamitsu, Keiichiro Toda, Ryoichi Horisaki and Takuro Ideguchi

Optics Letters 44, 3729-3732 (2019) Editors' Pick

Molecular contrast on phase-contrast microscope

Keiichiro Toda*, Miu Tamamitsu*, Ryoichi Horisaki and Takuro Ideguchi

Scientific Reports 9, 9957 (2019),  プレスリリース(東京大学),  UTokyo FOCUS

High‐speed broadband Fourier‐transform coherent anti‐stokes Raman scattering spectral microscopy

Ryo Kinegawa, Kotaro Hiramatsu, Kazuki Hashimoto, Venkata Ramaiah Badarla, Takuro Ideguchi, Keisuke Goda

Journal of Raman Spectroscopy 50, 1141-1146 (2019)

High-throughput label-free molecular fingerprinting flow cytometry 

Kotaro Hiramatsu*, Takuro Ideguchi*, Yusuke Yonamine, SangWook Lee, Yizhi Luo, Kazuki Hashimoto, Takuro Ito, Misa Hase, Jee-Woong Park, Yusuke Kasai, Shinya Sakuma, Takeshi Hayakawa, Fumihito Arai, Yu Hoshino and Keisuke Goda

Science Advances 5, aau0241 (2019),  プレスリリース(東京大学)

波形制御技術を用いた高速フーリエ変換分光法

橋本和樹、井手口拓郎

精密工学会誌85巻8号690頁(2019年8月号)

位相制御型フーリエ分光(2018年日本の光学研究)

橋本和樹、井手口拓郎

光学第48巻第6号213頁(2019年6月)

未来の科学を創る新規分光計測

井手口拓郎

学部生に伝える研究最前線・理学部ニュース(東京大学)2019年1月号

 

2018

Phase-controlled Fourier-transform spectroscopy

Kazuki Hashimoto and Takuro Ideguchi

Nature Communications 9, 4448 (2018),  プレスリリース(東京大学)

Microfluidic single-particle chemical analyzer with dual-comb coherent Raman spectroscopy

Takuro Ideguchi, Tasuku Nakamura, Shigekazu Takizawa, Miu Tamamitsu, Sangwook Lee, Kotaro Hiramatsu, Venkata Ramaiah Badarla, Jee-Woong Park, Yusuke Kasai, Takeshi Hayakawa, Shinya Sakuma, Fumihiko Arai and Keisuke Goda

Optics Letters 43, 4057-4060 (2018)  

Ultra-broadband rapid-scan Fourier-transform CARS spectroscopy with sub-10-fs optical pulses

Kazuki Hashimoto, Junko Omachi, and Takuro Ideguchi

Optics Express 26, 14307-14314 (2018) 

創薬における超高速ラマン分光法の活用

長島優、橋本和樹、大間知潤子、井手口拓郎

光アライアンス Vol.29, No. 6, 2126 (2018)

 

2017

Rapid-scan Fourier-transform coherent anti-Stokes Raman scattering spectroscopy with heterodyne detection

Kotaro Hiramatsu, Yizhi Luo, Takuro Ideguchi, and Keisuke Goda

Optics Letters 42, 4335-4338 (2017)

Ultrafast broadband Fourier-transform CARS spectroscopy at 50,000 spectra/s enabled by a scanning Fourier-domain delay line

Miu Tamamitsu, Yusuke Sakaki, Tasuku Nakamura, G. Krishna Podagatlapalli, Takuro Ideguchi, and Keisuke Goda

Vibrational Spectroscopy 91, 163-169 (2017)

Dual-Comb Spectroscopy

Takuro Ideguchi

Optics and Photonics News 28, 32-39 (2017)

Ultrafast broadband Fourier-transform CARS spectroscopy operating at 50,000 spectra/second

Miu Tamamitsu, Yusuke Sakaki, Tasuku Nakamura, G. Krishna Podagatlapalli, Takuro Ideguchi, Keisuke Goda

Proc. SPIE 10076, High-Speed Biomedical Imaging and Spectroscopy: Toward Big Data Instrumentation and Management II, 1007608 (February 22, 2017); doi:10.1117/12.2249726

 

高速ラマン計測による生命科学へのアプローチ

小関泰之、井手口拓郎、合田圭介

電気学会誌 Vol.137, No. 11, 768 (2017) 電気学会

24,000スペクトル毎秒で動作する広帯域コヒーレントラマン分光法

井手口拓郎、合田圭介

光学 46巻6号228 (9) (2017) 日本光学会

高速無標識バイオイメージングに向けたFourier transform CARS法

平松光太郎、井手口拓郎、合田圭介

光アライアンス Vol.28 June 2017 日本工業出版 

 

2016

Kerr-lens mode-locked bidirectional dual-comb ring laser for broadband dual-comb spectroscopy

Takuro Ideguchi, Tasuku Nakamura, Yohei Kobayashi, Keisuke Goda

Optica 3, 748-753 (2016)  

Nonlinear optical interactions in silicon waveguides

B. Kuyken, F. Leo, S. Clemmen, U. Dave, R. Van Laer, T. Ideguchi, H. Zhao, X. Liu, J. Safioui, S. Coen, S.P. Gorza, S. K. Selvaraja, S. Massar, R. M. Osgood Jr., P. Verheyen, J. Van Campenhout, R. Baets, W.M. J. Green, and G. Roelkens

Nanophotonics 5, 1-16 (2016) 

Broadband coherent Raman spectroscopy running at 24,000 spectra per second

Kazuki Hashimoto, Megumi Takahashi, Takuro Ideguchi, Keisuke Goda

Scientific Reports 6, 21036 (2016),  プレスリリース(東京大学),  プレスリリース(JST)c&en

High-throughput time-stretch microscopy with morphological and chemical specificity

Cheng Lei, Masashi Ugawa, Taisuke Nozawa, Takuro Ideguchi, Dino Di Carlo, Sadao Ota, Yasuyuki Ozeki, and Keisuke Goda

Proc. SPIE 9720, High-Speed Biomedical Imaging and Spectroscopy: Toward Big Data Instrumentation and Management, 97200X (March 7, 2016); doi:10.1117/12.2212670

高速コヒーレントラマン分光

井手口拓郎

分光研究vol.65, No.2, 113 (2016)

高速の化学分析が可能に!-高速広帯域コヒーレントラマン分光の実現

橋本和樹、井手口拓郎、合田圭介

月間化学Vol.71, No.6, 68-69 (2016)